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Over the years, numerous studies have highlighted the critical role of DNA methylation in the progression from precancerous conditions, such as cervical intraepithelial neoplasia (CIN), to CESC [261,262,263]

Yes, neurological complications from vitamin B12 deficiency, particularly subacute combined degeneration of the spinal cord, can become irreversible if left untreated

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A study focusing on the conjugation machinery for SUMOylation in response to low dose (100 M) ascorbate performed SUMO-1 IP followed by ESI-FT ICR MS in neuroblastoma cell line SH-SY5Y [162]

Sensitivity analysis The sensitivity analysis, which included both one-study-removed and cumulative analyses, showed that the results were robust and reliable

doi: 10.1128/mbio.00820-18 138